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Latest guidance reflects continuing prion concerns

The background to the DH’s 2016 updating of its guidance for surgical instruments, HTM 01-01.

A detailed look at the background to the Department of Health’s updating, in 2016, of its guidance for surgical instruments, HTM 01-01, Management and decontamination of surgical instruments (medical devices) used in acute care. As the authors, Jimmy Walker et al* explain, the changes were based on evidence from DH-commissioned research to understand the epidemiology of variant Creutzfeldt-Jacob Disease and the transmission of prion protein.

The Department of Health (England) updated its decontamination guidance for surgical instruments, Health Technical Memorandum 01-01, parts A-E, in 2016. The changes within the HTMs were based on evidence from research commissioned by the Department of Health to understand the epidemiology of variant Creutzfeldt-Jacob Disease and the transmission of prion protein, and were commissioned in response to the requirements of the Advisory Committee on Dangerous Pathogens (ACDP).1 This article will assist in understanding the evidence, with respect to prions, which was used to implement the ‘in situ’ measurements of protein, the advice from Advisory Committee on Dangerous Pathogens (ACDP), and the Chief Medical Officers (CMOs) (England and Devolved Nations), and the process through which the HTMs were written.

Independent, objective assessment of DH research

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